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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDHX
All Species:
12.73
Human Site:
S25
Identified Species:
20
UniProt:
O00330
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00330
NP_001128496.1
501
54122
S25
V
G
F
P
G
R
R
S
V
G
L
V
K
G
A
Chimpanzee
Pan troglodytes
XP_001149489
501
54051
S25
V
G
F
P
G
R
R
S
V
G
L
V
K
G
A
Rhesus Macaque
Macaca mulatta
XP_001109997
446
48686
D10
A
S
W
R
L
G
C
D
P
R
L
L
R
Y
L
Dog
Lupus familis
XP_533153
501
54075
R25
L
G
F
G
G
C
R
R
L
A
L
A
R
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKZ9
501
53981
S25
L
G
F
S
S
R
R
S
L
G
L
A
Q
G
A
Rat
Rattus norvegicus
P08461
632
67147
A34
G
P
R
T
G
P
A
A
V
R
C
G
S
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026358
502
53201
S25
R
G
G
R
P
V
L
S
A
G
L
A
V
P
A
Frog
Xenopus laevis
NP_001087423
478
50485
G25
G
G
L
R
T
H
S
G
E
C
S
L
R
A
L
Zebra Danio
Brachydanio rerio
NP_956854
490
51982
R31
A
G
L
Q
S
S
F
R
P
L
R
E
S
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624025
598
64649
M132
E
D
W
K
S
V
E
M
P
D
N
V
S
V
T
Nematode Worm
Caenorhab. elegans
Q19749
507
53448
G46
G
A
A
A
K
S
S
G
L
V
G
Q
V
A
R
Sea Urchin
Strong. purpuratus
XP_001177721
482
51019
S25
H
A
E
H
T
H
S
S
S
G
S
L
P
N
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WQF7
637
68844
S54
S
N
G
V
R
S
A
S
I
D
L
I
T
R
M
Baker's Yeast
Sacchar. cerevisiae
P12695
482
51800
Y28
L
R
L
Q
L
R
C
Y
A
S
Y
P
E
H
T
Red Bread Mold
Neurospora crassa
P20285
458
48601
P22
S
V
A
R
V
A
L
P
S
L
T
R
W
Y
A
Conservation
Percent
Protein Identity:
100
99.5
87
90.2
N.A.
85.2
34.4
N.A.
N.A.
72.1
58.8
58
N.A.
N.A.
36.4
37.2
47.3
Protein Similarity:
100
99.8
87.6
93.2
N.A.
91.4
49.6
N.A.
N.A.
82
73.4
73
N.A.
N.A.
51.6
56.7
63
P-Site Identity:
100
100
6.6
46.6
N.A.
60
20
N.A.
N.A.
33.3
6.6
6.6
N.A.
N.A.
6.6
0
13.3
P-Site Similarity:
100
100
26.6
66.6
N.A.
80
26.6
N.A.
N.A.
33.3
20
6.6
N.A.
N.A.
13.3
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.9
32.7
34.7
Protein Similarity:
N.A.
N.A.
N.A.
48.9
51.9
51.1
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
14
14
7
0
7
14
7
14
7
0
20
0
14
40
% A
% Cys:
0
0
0
0
0
7
14
0
0
7
7
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
7
0
14
0
0
0
0
0
% D
% Glu:
7
0
7
0
0
0
7
0
7
0
0
7
7
0
0
% E
% Phe:
0
0
27
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
20
47
14
7
27
7
0
14
0
34
7
7
0
34
0
% G
% His:
7
0
0
7
0
14
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
7
% I
% Lys:
0
0
0
7
7
0
0
0
0
0
0
0
14
0
7
% K
% Leu:
20
0
20
0
14
0
14
0
20
14
47
20
0
0
14
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% M
% Asn:
0
7
0
0
0
0
0
0
0
0
7
0
0
7
0
% N
% Pro:
0
7
0
14
7
7
0
7
20
0
0
7
7
14
0
% P
% Gln:
0
0
0
14
0
0
0
0
0
0
0
7
7
0
0
% Q
% Arg:
7
7
7
27
7
27
27
14
0
14
7
7
20
7
14
% R
% Ser:
14
7
0
7
20
20
20
40
14
7
14
0
20
0
0
% S
% Thr:
0
0
0
7
14
0
0
0
0
0
7
0
7
0
14
% T
% Val:
14
7
0
7
7
14
0
0
20
7
0
20
14
7
0
% V
% Trp:
0
0
14
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
7
0
0
14
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _